Project 3, Morphological Visualization and Assessment:

    Explore the envelope of tissue surrounding stimulation,
    recording and/or chemical delivery probes for histological
    evidence of deterioration of probe performance which has been
    observed electrophysiologically in vivo.

Collaborative Research Projects

In addition to internal projects, there are multiple collaborative
research projects with investigators outside the Center.
Collaborators contribute significantly toward improving and expanding
the use of the technology in areas including optimization of device
designs, evaluation of chronic connectors, interconnects and cranial
chambers, improvement of implantation methods, development of
protocols for chronic electrode site maintenance, testing of advanced
devices, and exploration of new application areas.

Here are links to webpages of some of our collaborators (more to come.....):

http://osiris.rutgers.edu/Buzsaki.html

    Gyorgy Buzsaki, M.D., Ph.D., Rutgers University, Neural network
    activity in the hippocampal formation

http://www.dbbs.wustl.edu/RIB/Highstein.html

    Steven Highstein, M.D. Ph.D., Washington University, Effects of
    microgravity upon the labyrinth

http://msewww.engin.umich.edu/people/milty/protein_polymers.html

    David Martin, Ph.D., University of Michigan, Microstructure and
    processing of bioactive protein polymers

http://www.med.umich.edu/khri/censys/jmiddleb.htm

    John Middlebrooks, Ph.D., University of Michigan, Cortical
    representation of auditory space

Service to investigators outside of the CNCT is provided in the forms
of distribution of probes, and training in their use.

Distribution has been a key component of the CNCT since its
inception.  In fact, it provided the main motivation for applying for
the first NIH NCRR grant in 1994. To receive probes, we require that
investigators fill out an application.  Details of the variety of
devices which we offer to the research public are outlined in a
catalog. Standard devices are provided packaged appropriate for acute

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